antisense therapy
The in vivo treatment of a genetic disease by blocking translation of a protein with a DNA or an RNA sequence that is complementary to a specific mRNA.

Glossary of Biotechnology for Food and Agriculture . 2015.

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  • Antisense therapy — is a form of treatment for genetic disorders or infections.When the genetic sequence of a particular gene is known to be causative of a particular disease, it is possible to synthesize a strand of nucleic acid (DNA, RNA or a chemical analogue)… …   Wikipedia

  • Antisense RNA — (aRNA) is single stranded RNA that is complementary to a messenger RNA (mRNA) strand transcribed within a cell. Antisense RNA may be introduced into a cell to inhibit translation of a complementary mRNA by base pairing to it and physically… …   Wikipedia

  • antisense — See a. DNA, a. RNA. * * * an·ti·sense an .tī .sens, an ti adj having a sequence complementary to a segment of genetic material specif of, being, relating to, or possessing a sequence of DNA or RNA that is complementary to and pairs with a… …   Medical dictionary

  • therapy — 1. The treatment of disease or disorder by any method. SEE ALSO: therapeutics. 2. In psychiatry, and clinical psychology, a short term for psychotherapy. SEE ALSO: psychotherapy …   Medical dictionary

  • antisense — ˌ adjective Etymology: anti (I) + sense (as in nonsense herein) : having a sequence complementary to a segment of genetic material ; specifically : of, being, relating to, or possessing a sequence of DNA or RNA that is complementary to and pairs… …   Useful english dictionary

  • antisense — adjective Etymology: anti + nonsense Date: 1977 having a sequence complementary to a segment of genetic material; specifically of, being, relating to, or possessing a sequence of DNA or RNA that is complementary to and pairs with a specific… …   New Collegiate Dictionary

  • antisense gene — /æntiˈsɛns dʒin/ (say antee sens jeen) noun a piece of DNA that is complementary to an existing gene which, when inserted into the genome, locks the expression of the primary gene; used in gene therapy …   Australian English dictionary

  • Gene therapy — using an Adenovirus vector. A new gene is inserted into an adenovirull. If the treatment is successful, the new gene will make a functional protein. Gene therapy is the insertion, alteration, or removal of genes within an individual s cells and… …   Wikipedia

  • Pharmacological gene therapy — is a new field that combines pharmacological therapy and gene therapy. It is used either to prevent a defective gene from producing its protein or to increase the concentration of normal protein produced in the body by insertion of DNA or RNA… …   Wikipedia

  • Sense (molecular biology) — In molecular biology and genetics, sense is a concept used to compare the polarity of nucleic acid molecules, such as DNA or RNA, to other nucleic acid molecules. Depending on the context within molecular biology, sense may have slightly… …   Wikipedia

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