excinuclease

The endonuclease-containing protein complex that excises a segment of damaged DNA during excision repair.

Glossary of Biotechnology for Food and Agriculture . 2015.

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  • Excinuclease — Excision endonuclease also known as excinuclease is the nuclease (enzyme) which performs the excision (cut) for nucleotide exchange in DNA repair. This particular enzyme is part of a mechanism that can repair in the G1 phase of the eukaryotic… …   Wikipedia

  • Helicase — Structure of E. coli helicase RuvA Helicases are a class of enzymes vital to all living organisms. They are motor proteins that move directionally along a nucleic acid phosphodiester backbone, separating two annealed nucleic acid strands (i.e.,… …   Wikipedia

  • DNA repair — For the journal, see DNA Repair (journal). DNA damage resulting in multiple broken chromosomes DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human… …   Wikipedia

  • Non-homologous end joining — (NHEJ) is a pathway that repairs double strand breaks in DNA. NHEJ is referred to as non homologous because the break ends are directly ligated without the need for a homologous template, in contrast to homologous recombination, which requires a… …   Wikipedia

  • Nucleotide excision repair — Diagram[1] Nucleotide excision repair is a DNA repair mechanism.[2] DNA constantly requires r …   Wikipedia

  • DNA mismatch repair — is a system for recognizing and repairing erroneous insertion, deletion and mis incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.[1][2] Mismatch repair is strand… …   Wikipedia

  • UvrABC endonuclease — is a multienzyme complex in E.coli bacteria involved in DNA repair mechanism by nucleotide excision repair and it is therefore sometimes called an excinuclease. This UvrABC repair process, sometimes called the short patch process, involves the… …   Wikipedia

  • MSH2 — MutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) PDB rendering based on 2o8b …   Wikipedia

  • Postreplication repair — is the repair of damage to the DNA that takes place after replication. Some example genes in humans include: BRCA2 and BRCA1 BLM NBS1 DNA damage prevents the normal enzymatic synthesis of DNA by the replication fork.[1][2][3][4] …   Wikipedia

  • ABC-exonuclease — (= ABC excinuclease) Enzyme complex, product of uvrA, uvrB and uvrC genes from E. coli that mediates incision and excision steps of DNA excision repair. Enzyme has the ability to recognize distortion in DNA structure caused by, eg. ultraviolet… …   Dictionary of molecular biology

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