p53 gene

A human tumour-suppressor transcription factor gene, damage or mutation to which is believed to be responsible for up to 60% of all human cancer tumours. If, in spite of the presence of p53 protein, a cell begins to divide uncontrollably following damage to its DNA, the p53 gene acts to prevent tumours by triggering apoptosis.

Glossary of Biotechnology for Food and Agriculture . 2015.

Look at other dictionaries:

  • p53 gene — a tumor suppressor gene that encodes the DNA binding p53 protein (q.v.). Mutations have been associated with malignant transformation of cells, including germline mutations in Li Fraumeni syndrome and sporadic somatic mutations …   Medical dictionary

  • p53 gene — A tumor suppressor gene that normally inhibits the growth of tumors. This gene is altered in many types of cancer …   English dictionary of cancer terms

  • P53 — (also known as protein 53 or tumor protein 53), is a transcription factor encoded by the TP53 gene. p53 is important in multicellular organisms, where it regulates the cell cycle and thus functions as a tumor suppressor that is involved in… …   Wikipedia

  • P53 — Bänder /Oberflächenmodell vpn p53 an DNA nach PDB  …   Deutsch Wikipedia

  • p53 — Bänder /Oberflächenmodell von p53 an DNA nach PDB  …   Deutsch Wikipedia

  • p53 — For the band and album of the same name, see P53 (band) and P53 (album). Tumor protein p53 PDB rendering based on 1TUP …   Wikipedia

  • p53 upregulated modulator of apoptosis — BCL2 binding component 3 Identifiers Symbols BBC3; FLJ42994; JFY1; PUMA External IDs …   Wikipedia

  • p53 — A tumor suppressor. The designation p53 stands for protein 53 kilodaltons in size. p53 is a specific protein produced by a gene that functions to suppress the growth of tumors. The p53 gene is the most commonly mutated gene known in human cancer …   Medical dictionary

  • P53 — est une protéine impliquée dans certains cancers. Sommaire 1 Historique 1.1 De 1979 à 1985 1.2 1985 1989 1.3 1989 2007 …   Wikipédia en Français

  • Gene suppresseur de tumeurs — Gène suppresseur de tumeurs Un gène suppresseur de tumeurs est un régulateur négatif de la prolifération cellulaire. Sommaire 1 Introduction 2 Les gènes suppresseurs de tumeurs 3 Cancers héréditaires …   Wikipédia en Français

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