single domain antibody

See: dAb

Glossary of Biotechnology for Food and Agriculture . 2015.

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  • Single-domain antibody — Ribbon diagram of a llama VHH domain. The extended CDR3 loop is coloured orange. A single domain antibody (sdAb, called Nanobody by Ablynx, the developer[1]) is an antibody fragment consisting …   Wikipedia

  • Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia

  • Single-chain variable fragment — Rotating scFv fragment with highlighted complementary determining regions (CDRs) …   Wikipedia

  • Single chain variable fragment — (scFv) is a fusion of the variable regions of the heavy and light chains of immunoglobulins, linked together with a short (usually serine, glycine) linker.This chimeric molecule retains the specificity of the original immunoglobulin, despite… …   Wikipedia

  • Protein domain — Pyruvate kinase, a protein from three domains (PDB 1pkn) A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three… …   Wikipedia

  • Monobody — The tenth fibronectin type III domain (human, PDB 1TTG) …   Wikipedia

  • Einzeldomänenantikörper — Strukturmodel eines Einzeldomänenantikörpers (Bändermodell). Einzeldomänenantikörper, auch Nanobodys oder Nanoantikörper genannt, sind Antikörperfragmente, die aus einer einzelnen, monomeren variablen Domäne eines Antikörpers aufgebaut sind. Im… …   Deutsch Wikipedia

  • Monoclonal antibodies — A general representation of the methods used to produce monoclonal antibodies. Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique… …   Wikipedia

  • DARPin — A DARPin with four ankyrin repeat motifs (PDB 1N0R) DARPins (an acronym for designed ankyrin repeat proteins) are genetically engineered antibody mimetic proteins typically exhibiting highly specific and high affinity target protein binding. They …   Wikipedia

  • Microantibody — A microantibody is an artificial short chain of amino acids copied from a fully functional natural antibody. Microantibodies can stop viruses such as HIV infecting cells in vitro.[1] Antibodies are produced naturally by the body and play a key… …   Wikipedia

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