chimeraplasty

A method designed to create defined alterations in DNA sequence at a target locus, with potential both for gene therapy and for investigating gene function. A synthetic nucleic acid that contains DNA interspersed with small amounts of RNA is introduced into the target cell, where it pairs with its target gene sequence and then triggers the cell's DNA repair machinery, resulting in the replacement of the native sequence by the synthetic one.

Glossary of Biotechnology for Food and Agriculture . 2015.

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  • Chimeraplasty — is a non viral method of gene therapy. Chimeraplasty changes DNA sequences using a synthetic strand of RNA and DNA. This strand of RNA and DNA is known as a chimeraplast. The chimeraplast enters a cell and attaches itself to the target gene. The… …   Wikipedia

  • Chimeraplasty — A method of gene therapy based upon the use of a molecule called a chimeraplast, a synthetic blend of DNA and the related molecule RNA, to trick the patient s own cells to remedy a gene defect. Chimeraplasts are made to match the patient s… …   Medical dictionary

  • List of genetics-related topics — This is a list of terms related to genetics. NOTOC # * 3 end * 5 end A * Acentric chromosome * Achondroplasia * Active site * Adam s Curse * Adaptation * Adenine * Adenosine * Adenovirus * Adenosine diphosphate (ADP) * Ala * Alagille syndrome *… …   Wikipedia

  • List of genetic engineering topics — NOTOC # 3 end 5 end A Acentric chromosome Achondroplasia Active site Adam s Curse Adaptation Adenine Adenosine Adenosine diphosphate Adenovirus ADP Ala Alagille syndrome Albino Alcoholism Alkylating agent Allele Allele frequency Alleles… …   Wikipedia

  • химерапластика — Метод введения гена в ДНК живых организмов или клеток, используя механизм генной репарации [http://www.dunwoodypress.com/148/PDF/Biotech Eng Rus.pdf] Тематики биотехнологии EN chimeraplasty …   Справочник технического переводчика

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